POLYMERS FOR DELIVERY OF FACTOR VIII AND/OR FACTOR IX

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专利权人:

Board of Regents; The University of Texas System

发明人:

Nicholas A. Peppas,Sarena D. Horava

申请号：

US16352325

公开号：

US20190275162A1

申请日:

2019.03.13

申请国别(地区):

US

年份:

2019

代理人:

摘要：

In some aspects, a composition comprising a pH-sensitive crosslinked copolymer of methacrylic acid and poly(ethylene glycol) monomethyl ether methacrylate and a therapeutic protein is provided. In some embodiments, the therapeutic protein is a high molecular weight protein such as factor VIII or factor IX. In some embodiments, the composition is orally administered to a patient to treat a disease or disorder such as, e.g., hemophilia.

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中国工程科技知识中心

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