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SUBLINGUAL PHARMACEUTICAL COMPOSITION CONTAINING NEUTRAL OIL
专利权人:
ЛондонФарма Лтд. (GB)
发明人:
БУЛИС Клайв (GB)
申请号:
RU2011139638/15
公开号:
RU2011139638A
申请日:
2010.04.23
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A pharmaceutical composition for sublingual drug delivery, comprising: a neutral oil; a drug soluble in said oil; wherein said drug is in solution in said oil at a concentration that provides the desired dose in the volume of the composition of not more than 1 ml; provided that said drug is not nitroglycerin. 2. The composition of claim 1, wherein said neutral oil contains glyceride. The composition of claim 2, wherein said glyceride contains triglyceride. The composition of claim 3, wherein said triglyceride contains migliol. 5. The composition of claim 4, wherein said migliol comprises migliol selected from the group consisting of: migliol 810; migliol 812; migliol 818; migliol 829; imigliol 840.6. The composition of claim 1, wherein said neutral oil contains an oil selected from the group consisting of: refined corn oil (Ph Eur (European Pharmacopoeia)); single-castor oil (Ph Eur); refined olive oil (Ph Eur) and refined rapeseed oil oil (Ph Eur). 7. The composition of claim 1, wherein said neutral oil contains an oil selected from the group consisting of: glycerol monooleates (Ph Eur); linoleoyl macrogolglycerides (Ph Eur); oleoyl macrogolglycerides (Ph Eur); vegetable fatty oils (Ph Eur); triglyceride-rich medium chain triglycerides (Ph Eur); coconut oil (Ph Eur); fractionated palm kernel oil (Ph Eur); hydrogenated cottonseed oil (Ph Eur); omega-3-marine triglycerides (Ph Eur); fish oil, rich in omega-3- acids (Ph Eur); cod liver oil (Ph Eur); diglycerides; monoglycerides; diglycerin. 8. The composition of claim 1, wherein said neutral oil contains a derivative1. Фармацевтическая композиция для сублингвальной доставки лекарственного средства, содержащая:нейтральное масло; илекарственное средство, растворимое в указанном масле;где указанное лекарственное средство находится в растворе в указанном масле в концентрации, обеспечивающей нужную дозу в объеме композиции не более чем 1 мл;при условии, что указанное лекарственное средство не является нитроглицерином.2.
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