МЭСИЛАГ Марк Дж. (US),СЯ Миндэ (US),СЮЙ Сяоцин (US)
申请号：
RU2011154368/04
公开号：
RU2011154368A
申请日:
2010.06.10
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. The compound of formula (I) where a is an integer from 0 to 3； each R is independently selected from the group consisting of halogen, hydroxy, cyano, lower alkyl, fluorinated lower alkyl, lower alkoxy, and fluorinated lower alkoxy； R is selected from the group, consisting of hydrogen, halogen, hydroxy, cyano, lower alkyl, fluorinated lower alkyl, lower alkoxy and fluorinated lower alkoxy； R is selected from the group consisting of alkyl, hydroxy-substituted lower alkyl, halogen-substituted lower alkyl, cycloalkyl- (lower alkyl) - and phenyl- (lower alkyl) -； alternatively, R and R, taken together, are R selected from the group consisting of lower alkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl, cycloalkyl- (lower alkyl) -, aryl- (lower alkyl) -, heteroaryl- (lower alkyl) - and heterocycloalkyl- (lower alkyl) -； where cycloalkyl, aryl, heteroaryl or heterocycloalkyl as a substituent or as part of a substituent, is optionally substituted with one or more substituents independently selected from the group consisting of halogen, lower alkyl halogen substituted lower alkyl, lower alkoxy, halogen substituted lower alkoxy, -C (O) OH, -C (O) O- (lower alkyl) and -C (O) -NRR； where R and R are each independently selected from the group consisting of hydrogen and lower alkyl； alternatively, R and R, together with a nitrogen atom, form a 5-6 membered saturated nitrogen-containing ring structure； R is selected from the group consisting of lower alkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl, cycloalkyl- (lower alkyl) -, aryl- (lower alkyl ) -, heteroaryl- (lower alkyl) - and heterocycloalkyl- (lower alkyl) -； where cycloalk1. Соединение формулы (I)где a представляет собой целое число от 0 до 3；каждый Rнезависимо выбран из группы, состоящей из галогена, гидрокси, циано, низшего алкила, фторированного низшего алкила, низшего алкокси и фторированного низшего алкокси；Rвыбран из группы, состоящей из водорода, галогена, гидрокси, циано, низшего алкила, фторированного
