SMITH NICHOLAS D.,KAHRAMAN MEHMET,GOVEK STEVEN P.,NAGASAWA JOHNNY Y.,LAI ANDILIY G.,JULIEN JACKALINE D.,HERBERT MARK R.,BONNEFOUS CELINE,DOUGLAS KARENSA L.
申请号：
NZ60779511
公开号：
NZ607795A
申请日:
2011.09.15
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Provided are compounds of Formula (I), preferably compounds of Formula (XII),wherein the variables are as defined in the specification. Examples of the compounds include (E)-3-(4-((E)-2-(2,4-Difluorophenyl)-1-(1H-indazol-5-y1)but-1-en-1-yl)phenyl)acrylic acid and (E)-3-(4-((E)-2-(2-Chloro-4-fluorophenyl)-1-(3-fluoro-1H-indazol-5-yl)but-1-en-lyl) phenyl)acrylic acid. The compounds are estrogen receptor modulators. The compounds may be useful in the treatment of cancers.
