An optical marker apparatus or device for tracking and compensating for patient motion during a medical imaging scan can comprise one or more optical markers, one or mounts, and a substrate. The one or more optical markers can be adapted to be detected by one or more detectors and/or cameras of a medical imaging scanner and/or motion tracking system. One or more mounts can be configured to attach the one or more markers to the substrate. The substrate, in turn, can be configured to be attached to one or more regions of a subject patient's body. For example, in some embodiments, a substrate can be adapted to be placed or otherwise attached over a nose bridge of a patient.