The Board of Regents of the University of Oklahoma
发明人:
Charles V. Rice
申请号：
US15736675
公开号：
US20180169140A1
申请日:
2016.06.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure describes compositions comprising β-lactam antibiotics and branched poly-ethylenimines (BPEI), having efficacy against various Gram-positive bacteria, for example Gram-positive bacteria having resistance against βlactam antibiotics, one non-limiting example of which is Methicillin-resistant Staphylococcus aureus (MRSA). The compositions result in the resensitization of such resistant bacterial strains to traditional antibiotic therapies such as β-lactam antibiotics.
