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Crystalline antifungal compounds
专利权人:
Antonio Cánovas Paredes;Anna Roig Serra;Kevin Meyer;Keith Lorimer;Elies Molins Grau;Javier Bartroli Orpi
发明人:
Antonio Cánovas Paredes,Javier Bartroli Orpi,Elies Molins Grau,Anna Roig Serra,Kevin Meyer,Keith Lorimer
申请号:
US12970297
公开号:
US08258296B2
申请日:
2010.12.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present subject matter relates to novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one represented by Formula II:, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.
来源网站:
中国工程科技知识中心
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