BRAUN, MATHIAS,BUSACCA, CARL ALAN,CHEN, FENG-JING,GUMP, EDWIN LOUIS,MAJESKA, JENNESS B.,PENNINO, SCOTT,QIU, FENGHE,VILLAGRA, MARIA FERNANDA
申请号：
CA2861041
公开号：
CA2861041A1
申请日:
2013.01.10
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Described are various methods for stabilizing pharmaceutical formulations of a specific Hepatitis C Viral (HCV) inhibitor against the formation of a particular genotoxic degradation product. Such methods include temperature control, moisture control, excipient control, capsule shell control, basification and a reconstitution approach.
