ANDREA EICKER,ANDREAS SCHEIDIG,CARL INNES WEBSTER,CHRISTOPH MAHLERT,CLAUDIA GOTZBERGER-SCHAD,JAN TEBBE,JOANA GRUDZINSKA,JOHAN PER WALLIN,JORG BIRKENFELD,JOSI INNIG,LUTZ ULRICH JOCHEN WILHELM JERMUTUS
申请号：
BRPI1014942
公开号：
BRPI1014942A2
申请日:
2010.06.21
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention relates to polypeptides comprising protease variants of wild type human neprilysin having an altered specificity and/or activity. In particular the present invention relates to polypeptides comprising protease variants derived from human neprilysin having an increased specificity and/or activity against certain substrates, in particular against amyloid beta.
