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LONG ACTING LUTEINIZING HORMONE (LH) COMPOUND
专利权人:
ARTS BIOLOGICS A/S
发明人:
Peter Nordkild,Svend Lindenberg,Claus Yding Andersen,Kim Vilbour Andersen
申请号:
US15168001
公开号:
US20170000895A1
申请日:
2016.05.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a long acting biologically active luteinizing hormone (LH) compound comprising an LH agonist linked to a pharmaceutically acceptable molecule providing an in vivo plasma half-life of the LH agonist or LH compound which is increased substantially compared to the in vivo plasma half-life of an LH agonist administered in the same manner as the LH compound. The present invention relates to methods for controlled ovarian stimulation which can be used in conjunction with assisted reproduction technologies such as in vitro fertilisation, intra cytoplasmatic sperm injection, intra uterine insemination and in vitro maturation. In other aspects the invention relates to methods for inducing folliculogenesis and methods for providing luteal support for the corpora lutea.
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