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棒狀皮膚外用固形基材
专利权人:
LTD.;NISSAN CHEMICAL INDUSTRIES
发明人:
SAKATA, MIZUKI,坂田瑞希,IMOTO, TAKAYUKI,井本鹰行,井本鷹行
申请号:
TW106144960
公开号:
TW201834634A
申请日:
2017.12.21
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
To provide a solid preparation base that can be prevented from being suffering from "sweating" over time, which is an important property required for a stick-type solid preparation base for external application to skin which can be used for cosmetics and the like. A stick-type solid preparation base for external application to skin, which comprises: a lipid peptide-type compound comprising at least one component selected from a compound represented by formula (1) and an analogous compound or a pharmaceutically usable salt thereof; a surfactant; water; an oily base material; and a saturated or unsaturated monohydric alcohol having 8 to 30 carbon atoms. (In the formula, R1 represents an aliphatic group having 9 to 23 carbon atoms; R2 represents a hydrogen atom, or an alkyl group which has 1 to 4 carbon atoms and may have a branched chain having 1 or 2 carbon atoms; R3 represents a -(CH2)n-X group; n represents a numerical value of 1 to 4; and X represents an amino group, a guanidino group, a -CONH2 group, or a 5-membered ring or a 6-membered ring each of which may have 1 to 3 nitrogen atoms or a condensed heterocyclic ring composed of the 5-membered ring and the 6-membered ring).本發明課題在於提供一種可防止隨時間經過之「冒汗」的固形基材;此防止冒汗之特性係作為針對化妝品等之棒狀皮膚外用固形基材極為重要的特性。   解決手段為一種棒狀皮膚外用固形基材,其係包含:由下述式(1)所示之化合物及其類似化合物或彼等之藥學上可使用之鹽中的至少一種所構成的脂質肽型化合物、界面活性劑、水、油性基劑與碳原子數8至30之飽和或不飽和一元醇;(式中,R1表示碳原子數9至23之脂肪族基,R2表示氫原子、或可具有碳原子數1或者2之支鏈的碳原子數1至4之烷基,R3表示-(CH2)n-X基,n表示1至4之數,X表示胺基、胍基、-CONH2基、或可具有1至3個氮原子之五員環或者六員環或由五員環與六員環所構成的縮合雜環)。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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