CHRISTOPHER, MATTHEW, P.,FRADERA LLINAS, FRANCESC XAVIER,MACHACEK, MICHELLE,MARTINEZ, MICHELLE,REUTERSHAN, MICHAEL HALE,SHIZUKA, MANAMI,SUN, BINYUAN,THOMPSON, CHRISTOPHER FRANCIS,TROTTER, B. WESLEY,VO
申请号:
EP14749379
公开号:
EP2953470A4
申请日:
2014.02.04
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides 2,6,7 substituted purines as described herein or a pharmaceutically acceptable salt thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.