The present invention relates to a complex of agomelatine and cyclodextrin, a composition comprising said complex, a process of preparing said complex and a pharmaceutical formulation comprising said complex or composition.La présente invention concerne un complexe dagomélatine et de cyclodextrine, une composition comprenant ledit complexe, un procédé de préparation dudit complexe et une formulation pharmaceutique comprenant ledit complexe ou ladite composition.