FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MINAS GERAIS-FAPEMIG;UNIVERSIDADE FEDERAL DE VIÇOSA;PATSOS ENDUSTRIA E COMERCIO DE PRODUTOS BIOTECNOLÓGICOS LTDA
发明人:
Joaquim Hernan Patarroyo Salcedo,Marlene Isabel Vargas Viloria,Sidimar Sossal,Leandro Silva de Araujo,Gabriel Andres Tafur Gomez,Marcio Alberto Dias Mendes
申请号：
US15029982
公开号：
US20160237127A1
申请日:
2014.10.15
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to the field of biotechnology and genetic engineering, and particularly to the expression of recombinant peptides. The inoculation thereof in cattle results in the production of an immune response capable of adversely affecting Rhipicephalus microplus ticks, which feed on the inoculated cattle, decreasing the number and reproductive capacity of this tick species. Such recombinant immunogen can be used as an effective vaccine for tick control. The technical goal is the design and construction of two synthetic genes made with preferred codons for Pichia pastoris and expression thereof from a recombinant peptide, which consists in a continuous sequence and of a recombinant peptide, respectively, and the drug composition based of said recombinant polypeptide.
