Michael BALTEZOR,Sam CAMPBELL,Charles J. DECEDUE,Gere S. DIZEREGA,William JOHNSTON,Matthew MCCLOREY,James VERCO
申请号:
US16239530
公开号:
US20190365698A1
申请日:
2019.01.04
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed are methods useful for the therapeutic treatment of cancerous solid tumors by the administration of an antineoplastic agent, wherein the antineoplastic agent resides at the tumor site exposing the tumor to the antineoplastic agent for a sustained amount of time sufficient to stimulate the endogenous immune system of the subject resulting in the production of tumoricidal cells and infiltration of the tumoricidal cells in and around the tumor site at a level sufficient to treat the tumor. The methods include local administration methods such as topical application, pulmonary administration, intratumoral injection, and intraperitoneal injection.