ANTICORPS ANTI-PCSK9, FRAGMENT DE LIAISON A L'ANTIGENE ASSOCIE ET APPLICATION MEDICALE ASSOCIEE

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专利权人:

JIANGSU HENGRUI MEDICINE CO.; LTD.;SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.;JIANGSU HENGRUI MEDICINE CO., LTD.

发明人:

QU, XIANGDONG,YE, XIN,XU, SHAOYU,YUAN, BEI,CUI, DONGBING,HU, QIYUE,ZHANG, LEI,XU, ZHIBIN,TAO, WEIKANG,ZHANG, LIANSHAN,SUN, PIAOYANG

申请号：

CA3009904

公开号：

CA3009904A1

申请日:

2016.12.20

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention provides a PCSK9 antibody, an antigen-binding fragment thereof, and a medicinal application thereof. Provided in the invention is a chimeric antibody and a humanized antibody, both comprising a CDR of the PCSK9 antibody, and a pharmaceutical composition comprising the PCSK9 antibody and an antigen-binding fragment thereof, and an application of the PCSK9 antibody as a lipid-lowering agent. The invention specifically relates to an application of a humanized PCSK9 antibody for preparing a pharmaceutical drug to treat a PCSK9-induced disease or symptom.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/