Federalnoe gosudarstvennoe byudzhetnoe uchrezhdenie "Natsionalnyj meditsinskij issledovatelskij tsentr transplantologii i iskusstvennykh organov imeni akademika V.I. Shumakova" Ministerstva zdravookhr
发明人:
Bondarenko Denis Mikhajlovich (RU),Бондаренко Денис Михайлович (RU),Afanasev Andrej Vladimirovich (RU),Афанасьев Андрей Владимирович (RU),Akopov Grigorij Aleksandrovich (RU),Акопов Григорий Александро
申请号：
RU2019136315
公开号：
RU0002724871C1
申请日:
2019.11.12
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to cardiovascular surgery, medical equipment. System comprising interconnected physiological and perfusion units is used. First, artificial blood circulation (ABC) is performed in parallel to antegrade pharmaco-cholera cardioplegia. Circulation reservoir is filled with cardioplegic solution, main line perfusion ports are connected to left coronary and right coronary arteries, and connection between physiological and perfusion units is blocked. That is followed by circulatory arrest and selective bilateral antegrade perfusion of the brain through a left common carotid artery (lCCA) and a brachiocephalic trunk (BCT), for which the arterial line is closed, a connection is opened between the physiological and perfusion units, the cardioplegic solution is displaced with the perfusate of the physiological unit, the circulation reservoir is disconnected, ports of main lines for perfusion of the main vessel are connected to the lCCA and BCT of the patient. Brain perfusion is performed at temperature 27–28 °C with separate delivery of oxygenated blood by lCCA and BCT, maintaining pressure of 50–70 mm Hg and cerebral perfusion rate of at least 250 ml/min separately along the main vessel perfusion lines. After the circulatory arrest is completed, the ABC is continued while the patient is warmed, and the cerebrum perfusion is continued at 27–28 °C, maintaining said perfusion parameters.EFFECT: method enables performing ABC with cardioplegia, perfusion of cerebrum using one universal system, provides prevention of neurological complications.1 cl, 4 dwg, 1 ex, 1 tblИзобретение относится к медицине, а именно к сердечно-сосудистой хирургии, медицинской технике. Используют систему, включающую соединенные между собой физиологический и перфузионный блоки. Сначала проводят искусственное кровообращение (ИК) параллельно с антеградной фармакохолодовой кардиоплегией. Циркуляционный резервуар заполняют кардиоплегическим раствор
