YANG, Guohan,HAI, Ton,MELNICK, Bennett,SANDERS, Paul,JIANG, Cong,QUINN, Catherine,LI, Jie,AMBROISE, Arounaguiry,BROWN, Larry
申请号：
ES09791780
公开号：
ES2617868T3
申请日:
2009.08.21
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of Formula I: ** ** Formula wherein Y is selected from the group consisting of halide, N3, -CN, RO-, NH2O-, NHRO-, NR2O-, RCO2-, ROCO2-, RNCO2-, RS-, RC (S) O-, RCS2-, RSC (O) S-, RSCS2- RSCO2-, ROC (S) O-, ROCS2-, RSO2-, RSO3-, ROSO2-, ROSO3-, RPO3-, ROPO3-, imidazolyl, N-triazolyl, N-benzotriazolyl, benzotriazolyloxy, imidazolyloxy, N-imidazolinone, N-imidazolone, N-imidazolinetiona, N-succinimidyl, N-phthalimidyl, N-succinimidyloxy, N-ftalimidiloxi, N- (5- norbornene-2,3-dicarboxiimidiloxi), 2-thioxothiazolidin-3-yl, -ON> = C (CN) R, 2-pyridyloxy, phenoxy, p-chlorophenoxy, p-nitrophenoxy, trichlorophenoxy and pentachlorophenoxy R is an alkyl group or an aryl group X is selected from the group consisting of O, S and NR3 n is 1, 2 or 3 The polymer is a soluble polymer nonpeptidic water R1 and R2 are independently selected from the group consisting of hydrogen, (C1-C6) alkylenearyl (C1-C6) and aryl, with the proviso that at least one of R1 and R2 is different from hydrogen and R3 is selected from the group consisting of hydrogen, (C1-C6) alkylenearyl (C1-C6) and aryl.Un compuesto de Fórmula I:**Fórmula** en la que Y se selecciona del grupo que consiste en haluro, N3, -CN, RO-, NH2O-, NHRO-, NR2O-, RCO2-, ROCO2-, RNCO2-, RS-, RC(S)O-, RCS2-, RSC(O)S-, RSCS2- RSCO2-, ROC(S)O-, ROCS2-, RSO2-, RSO3-, ROSO2-, ROSO3-, RPO3-, ROPO3-, imidazolilo, N-triazolilo, N-benzotriazolilo, benzotriazoliloxi, imidazoliloxi, N-imidazolinona, N-imidazolona, N-imidazolinetiona, N-succinimidilo, N-ftalimidilo, N-succinimidiloxi, N-ftalimidiloxi, N-(5-norbornen-2,3-dicarboxiimidiloxi), 2-tioxotiazolidin-3-ilo, -ON>=C(CN)R, 2-piridiloxi, fenoxi, p-clorofenoxi, p-nitrofenoxi, triclorofenoxi y pentaclorofenoxi R es un grupo alquilo o un grupo arilo X se selecciona del grupo que consiste en O, S y NR3 n es 1, 2 o 3 EL POLÍMERO es un polímero soluble en agua no peptídico R1 y R2 se seleccionan independientemente entre el grupo que consiste en hidrógeno, alquilo (C1-C6), alquilenarilo
