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Carbidopa/levodopa gastroretentive drug delivery
专利权人:
INTEC PHARMA LTD.
发明人:
Nadav Navon,Eytan Moor,David Kirmayer,Elena Kluev,Giora Carni
申请号:
US14715077
公开号:
US09259387B2
申请日:
2015.05.18
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A gastroretentive drug formulation for the sustained release of an active agent in the gastrointestinal tract comprises an internal layer or compartment comprising an active agent and one or more pharmaceutical excipients, of which at least one is a polymer and two membranes forming together an envelope around the inner membrane, each membrane comprising at least one polymeric combination of an enteric polymer which is not soluble in gastric juice, and an hydrophilic swelling polymer, and at least one plasticizer.
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