A cartridge (10), comprising a housing (12) defining a recess (22) therein and an absorbent element (14) within said recess (22) on which is held an allergen, which is to be tested on the skin of a person. An applicator (40) for the storage of multiple cartridges (10a) to (10e), and the application of an allergen held in the absorbent element (14) onto the skin of a person. The applicator (40) comprises a substantially tubular housing (41), with a substantially cylindrical compartment (45) within, able to hold multiple cartridges (10a) to (10e). The cartridges (10) are pushed towards an open end (41b) of the housing (41) by a cartridge advancement means (52), and are physically prevented from being ejected by a cartridge retaining means (62), and in this case, a secondary cartridge retaining means (64). The cartridge retaining means (62) and secondary cartridge retaining (64) means can be disengaged by a user in order to eject a lead cartridge (10a) once it has been used. A following cartridge (10b) is then moved to the front of the applicator (40), by the cartridge advancement means (52), ready for the next use. A method for application of an allergen onto the skin of a person by use of an applicator (40) and cartridge (10) is also provided.Linvention concerne une cartouche (10), comprenant un boîtier (12) définissant un évidement (22) à lintérieur et un élément absorbant (14) à lintérieur dudit évidement (22) sur lequel est retenu un allergène, qui doit être testé sur la peau dune personne. Linvention concerne un applicateur (40) pour le stockage de multiples cartouches (10a) à (10e), et lapplication dun allergène retenu dans lélément absorbant (14) sur la peau dune personne. Lapplicateur (40) comprend un boîtier sensiblement tubulaire (41), avec à lintérieur un compartiment sensiblement cylindrique, (45), capable de contenir de multiples cartouches (10a) à (10e). Les cartouches (10) sont poussées vers une extrémité ouverte (41b) du boîtier (41) par un moyen davan