Ross L. Levine,Omar Abdel-Waheb,Jay P. Patel,Mithat Gonen
申请号：
US14384580
公开号：
US20150031641A1
申请日:
2013.03.11
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Gene mutations are associated with the progression of acute myeloid leukemia (AML). The invention relates to methods and systems for evaluating the progression of AML based on these gene mutations. The present invention also relates to methods and compositions for treating AML patients by modulating the expression or activity of certain genes involved in AML progression and/or their encoded proteins. The invention further relates to methods and compositions for determining the responsiveness of an AML patient to induction chemotherapy therapy.
