The present invention relates to an adhesive composition applicable to skin comprising a base polymer comprising at least one homopolymer and/or copolymer and silica. This invention also relates to a medical adhesive device including such adhesive composition. The present invention relates to adhesive compositions applicable to skin and their use in a medical adhesive device. The adhesive compositions carry unique features, including, e.g., excellent adhesion, skin friendliness (e.g. hypoallergenicity), repositionabilty, substantially painless and residue-free detachment after application, and the ability to initiate natural antimicrobial activities.
