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COMPOSITIONS AND METHODS FOR UTILIZING CONDITIONALLY LETHAL GENES
专利权人:
VIAGENE; INC.
发明人:
BARBER, JACK R.,GRUBER, HARRY E.,JOLLY, DOUGLAS J.
申请号:
CA2158936
公开号:
CA2158936C
申请日:
1994.11.18
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides recombinant viral vectors carrying a vectorconstruct which directs the expression of a gene product (e.g., HSVTK) thatactivates a compound with little or no cytotoxicity into a toxic product. Alsoprovided are methods of destroying or inhibiting pathogenic agents in a warmblooded animal, comprising the step of administering to the animal a viralvector such as that described above, in order to inhibit or destroy thepathogenic agent.
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