Method for synthesizing highly sulfated chondroitin sulfates, highly sulfated chondroitin sulfates, and analytical reagents

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专利权人:

学校法人;愛知医科大学

发明人:

杉浦 信夫

申请号：

JP2011018629

公开号：

JP5885136B2

申请日:

2011.01.31

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a method for synthesizing highly sulfated chondroitin sulfates.SOLUTION: The method for synthesizing highly sulfated chondroitin sulfates includes: a step (A1) of forming A structure of a chondroitin sulfate by making sulfotransferase (C4ST-1) act on the chondroitin； a step (A2) of forming E structure of a chondroitin sulfate by making a sulfotransferase (Ga1NAc4S-6ST) act on the A structure； and a step (A3) of forming triS structure of a chondroitin sulfate by making a sulfotransferase UST act on the E structure.

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中国工程科技知识中心

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