Gary Peter Bembridge,Chun-wa Chung,Susannah Karen Ford,Ian Kirby,Ruth McAdam,Maria Feeney
申请号：
US14540247
公开号：
US09605063B2
申请日:
2014.11.13
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanizing antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
