THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;MARINE POLYMER TECHNOLOGIES INC.
发明人:
PAVLAKIS, GEORGE N.,VOURNAKIS, JOHN N.,FELBER, BARBARA K.,FINKIELSZTEIN, SERGIO
申请号:
CA2691785
公开号:
CA2691785C
申请日:
2008.06.27
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to agents that modulate interleukin-15 ("IL-15")signal transduction or function ("Therapeutic Agents")and the use or those agents to modulate immune function. The TherapeuticAgents target the interaction betweenIL-15 and its receptor and modulate IL-15-induced signal transduction. TheTherapeutic Agents may be formulated with polymers,such as poly-.beta.- 1 - ~4-N-acetylglucosamine. for administration to a humansubject to modulate IL-15-mediated immune function.