A medical signal processing device receives an image signal in accordance with a result of examining inside of a subject and processes the image signal. The medical signal processing device includes a signal processing unit configured to generate a plurality of transmission image signals from the image signal. The transmission image signals each include a plurality of distributed image signals obtained by distributing the image signal, at least any of the transmission image signals includes, as auxiliary data, data of at least part of distributed image signals different from the distributed image signals included in the transmission image signal, and the transmission image signals are transmitted to an external medical control device through a plurality of respective signal transmission paths.