REED KENNETH JOSEPH,COSTANZO WENDI ANN,ERLICHMAN JOSEPH SAMUEL,BELL ERIC LESLIE
申请号：
IN10550DEN2014
公开号：
IN10550DEN2014A
申请日:
2014.12.10
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
A process for making nanoparticles of biocompatible materials is described wherein an aqueous reaction mixture comprising cerous ion citric acid and ethylenediaminetetraacetic acid in a predetermined ratio an oxidant and water is provided along with temperature conditions to directly form without isolation a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases such as stroke relapse/remitting multiple sclerosis chronic progressive multiple sclerosis amyotrophic lateral sclerosis and ischemic reperfusion injury.
