SALTS OF KUKOAMINE B, PREPARATION METHOD AND USE THEREOF

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专利权人:

天津紅日薬業株式有限公司;THE;中国人民解放軍第三軍医大学第一付属病院;FIRST AFFILIATED HOSPITAL THIRD MILITARY MEDICAL UNIVERSITY PLA;TIANJIN CHASESUN PHARMACEUTICAL CO LTD;FIRST AFFILIATED HOSPITAL THIRD MILITARY MEDICAL UNIVERSITY PLA:THE

发明人:

ZHENG JIANG,鄭江,ZHENG XINCHUAN,鄭新川,LIU XIN,劉シン,ZHOU HONG,周紅,WANG NING,王寧,CAO HONGWEI,曹紅衛,LI YAN,李彦,LU YONGLING,魯永玲,ZHAO KECEN,趙苛岑,YANG JINGCHENG,楊景程,YANG YANG,楊陽,ZHU YUANFENG,祝元鋒,WEI GUO,衛国,HUANG MIN,黄

申请号：

JP2015178139

公开号：

JP2016029053A

申请日:

2015.09.10

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide salts of kukoamine B for use in preparation of drugs for preventing and treating pyemia and pharmaceutical compositions containing salts of kukoamine B.SOLUTION: Use of salts of kukoamine B in preparation of drugs for preventing and treating pyemia is provided, the kukoamine B is separated from a crude drug "Lycii Radicis Cortex," a dried root cortex of Lycium chinensis, a solanaceous plant, the chemical structure of the salt being represented by the following formula. The salt of kukoamine B is characterized in that it neutralizes lipopolysaccharide (LPS) in vitro.SELECTED DRAWING: Figure 1【課題】膿毒症の予防と治療をする薬物を製造するためのクコアミンＢの塩、及びクコアミンＢの塩含有薬物組成物の応用の提供。【解決手段】オス科のクコの根皮の日干し物の生薬「地骨皮」より分離される下記式で表されるクコアミンBの塩の、膿毒症を予防と治療する薬物の製造における応用であって、前記クコアミンBの塩は体外でリポ多糖（ＬＰＳ）を中和することを特徴とするクコアミンBの塩の応用。【選択図】図１

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/