PROBLEM TO BE SOLVED: To provide a technique which improves the elutability of propionic acid-based NSAIDs in a tablet containing propionic acid-based NSAIDs and an aluminum-compounded antacid such as an aluminum-compounded inorganic metal salt after the tablet is stored in a simple manner without causing troubles in production.SOLUTION: A tablet includes (A) propionic acid-based non-steroidal anti-inflammatory drugs (NSAIDs), (B) an aluminum-compounded inorganic metal salt, and (C) a high-molecular compound having carboxy groups unsubstituted with metal ions, is one layered or two layered, has a content mass ratio as expressed by (C)/(B) of 0.3-3, and includes components (A), (B) and (C) in the same layer (provided that the components may be compounded as granulated but granules containing both components (A) and (B) at the same time are excluded).COPYRIGHT: (C)2014,JPO&INPIT【課題】プロピオン酸系NSAIDs及びアルミニウム配合無機金属塩等のアルミニウム配合系の制酸剤を含有する錠剤中における、錠剤保存後のプロピオン酸系NSAIDsの溶出性を、簡便にかつ製造時のトラブルを回避して、向上させる技術を提供する。【解決手段】(A)プロピオン酸系非ステロイド性抗炎症薬(NSAIDs)、(B)アルミニウム配合無機金属塩、(C)金属イオンで置換されていないカルボキシル基を有する高分子化合物を含有し、1層又は2層以上の錠剤であって、(C)/(B)で表される含有質量比が0.3~3であり、(A)、(B)及び(C)成分が同じ層に存在する錠剤(但し、上記成分は造粒物として配合されてもよいが、(A)及び(B)成分が同じ造粒物中に含まれるものを除く。)。【選択図】なし
