Hilman, Jurgen,Lipp, Ralph,Heithecker, Renate,Heil, Wolfgang
申请号：
AU2014227490
公开号：
AU2014227490A1
申请日:
2014.09.18
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2014227490A120141009.pdf#####H:\tzm\Interwoven\NRPortbl\DCC\TZM\6753328_l.DOC- 18/09/2014 PHARMACEUTICAL COMBINATION OF ETHINYLESTRADIOL AND DROSPIRENONE FOR USE AS A CONTRACEPTIVE ABSTRACT A pharmaceutical composition comprises, as a first active agent, 6P, 7P, 15p, 16pdimethylene-3-oxo-17a-pregen-4-ene-21, 17-carbolactone (drospirenone) in an amount corresponding to a daily dosage, on administration of the composition, of from about 2 mg to about 4 mg, and, as a second active agent, 17a-ethinylestradiol (ethinylestradiol) in an amount corresponding to a daily dosage of from about 0.01 mg to about 0.05 mg, together with one or more pharmaceutically acceptable carriers or excipients. In a specific embodiment, the composition consists of a number of separately packaged and individually removable daily dosage units placed in a packaging unit and intended for oral administration for a period of at least 21 consecutive days, wherein said daily dosage units comprise the combination of drospirenone and ethinylestradiol. The composition may further comprise 7 or less daily dosage units containing no active agent or containing ethinylestradiol alone.
