Helen Sabzevari,Simon Metenou,ChangHung Chen,Rutul R. Shah
申请号:
US16506981
公开号:
US20200048351A1
申请日:
2019.07.09
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein is a composition comprising a fusion protein or a fragment or a variant thereof comprising an anti-PD1 antibody or a fragment/variant thereof and a TGF-β trap. Provided herein is a composition comprising a fusion protein or a fragment thereof or a variant thereof comprising an anti-PD1 antibody or a fragment/variant thereof and a ADA2 polypeptide. Also provided herein are methods of using the composition in treating cancer.