Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof

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专利权人:

Takayuki Okuno

发明人:

Takayuki Okuno,Masahiro Sakagami

申请号：

US12766458

公开号：

US08227618B2

申请日:

2010.04.23

申请国别(地区):

US

年份:

2012

代理人:

摘要：

This invention provides an anorectic or anti-obesity composition comprising a compound of the formula (I):formula (I):a pharmaceutically acceptable salt or solvate thereof,whereinR1 is optionally substituted lower alkyl,Y is —S(O)n- wherein n is 1 or 2, or —CO—,R2 is hydrogen or lower alkyl,R7 is hydrogen or lower alkyl,X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, andZ is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like.

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