Methods and devices are provided that are effective to remove an obstruction in a human airway related to snoring and/or OSA. In one embodiment, the device includes mouthpiece having a hollow body configured to be disposed in a users mouth. The body includes superior and inferior outer surfaces as well as anterior and posterior surfaces, a channel configured to receive a users teeth formed in at least one of the superior and inferior surfaces, an inner cavity formed between the superior, inferior, anterior, and posterior surfaces, and at least one aperture formed in the posterior surface that extends into the inner cavity. In one exemplary embodiment the at least one aperture is oriented to extend away from the users teeth and toward a users tongue when the mouthpiece is in use. In another embodiment, the hollow body is substantially c-shaped, and the at least one aperture includes a plurality of apertures spaced a distance apart from one another along the posterior surface between first and second terminal ends of the c-shaped inner portion of the hollow body. In still another embodiment, the mouthpiece includes an outer portion having an opening extending therethrough such that the outer portion is coupled to the hollow body and is in fluid communication with the cavity in the hollow body. A one-way valve can be disposed in the opening and can be configured to allow air to flow out of a users oral cavity when the mouthpiece is in use.
