AGENSYS; INC.;AGENSYS, INC.;SEATTLE GENETICS, INC.
发明人:
SATPAEV, DAULET,MORRISON, ROBERT KENDALL,MORRISON, KAREN JANE MEYRICK,GUDAS, JEAN,JAKOBOVITS, AYA,TORGOV, MICHAEL,AN, ZILI
申请号:
CA2811644
公开号:
CA2811644A1
申请日:
2011.09.29
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.