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Fused heterocyclic derivative and use thereof
专利权人:
Nobuhiro Fujii
发明人:
Nobuhiro Fujii,Yuya Oguro,Satoshi Sasaki,Shigeru Kondo
申请号:
US12919413
公开号:
US08399449B2
申请日:
2009.02.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a compound having a superior Smo inhibitory activity and lower toxicity, which is sufficiently satisfactory as a pharmaceutical product. The present invention provides a compound represented by the formula (I) wherein ring A is 5- to 7-membered ring optionally having substituent(s), where substituents are optionally bonded to each other to form a ring X is O, S or NR1 (R1 is a hydrogen atom or a hydrocarbon group optionally having substituent(s)) R2 is carbamoyl optionally having substituent(s) and R3 is hydroxy optionally having substituent(s), or a salt thereof.
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