TAO, Zhi-Fu,DOHERTY, George,WANG, Xilu,SULLIVAN, Gerard M.,SONG, Xiaohong,KUNZER, Aaron R.,WENDT, Michael D.,MARIN, Violeta L.,FREY, Robin R.,CULLEN, Steve C.,WELCH, Dennie S.,SHEN, Xiaoqiang,BENNETT,
申请号:
SG11201704710P
公开号:
SG11201704710PA
申请日:
2015.12.09
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
The present disclosure concerns Bcl-xL inhibitors having low cell permeability, antibody drug conjugates (ADCs) comprising the inhibitors, synthons useful for synthesizing the ADCs, compositions comprising the inhibitors or ADCs, and various methods of using the inhibitors and ADCs.