脂肪酸醯胺水解酶抑制劑农业专利-农业专业知识服务系统

发明人:: ADAMS, JULIAN,亚当斯　朱利安,亞當斯　朱利安,BEHNKE, MARK L.,班奇　马克Ｌ.,班奇　馬克Ｌ.,CASTRO, ALFREDO C.,卡斯楚　阿佛列多Ｃ.,EVANS, CATHERINE A.,伊凡斯　凯瑟琳Ａ.,伊凡斯　凱瑟琳Ａ.,GRENIER, LOUIS,格林尼尔　路易斯,格林尼爾　路易斯,GROGAN, MICHAEL J.,葛罗根　麦,亚当斯朱利安,亞當斯朱利安,班奇马克L.,班奇馬克L.,卡斯楚阿佛列多C.,伊凡斯凯瑟琳A.,伊凡斯凱瑟琳A.,格林尼尔路易斯,格林尼爾路易斯,葛罗根麦

摘要：: The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III).The present invention also provides methods for treating conditions associated with excessive FAAH activity by administering a therapeutically effective amount of a provided compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH in a patient by administering a therapeutically effective amount of a compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof.本發明提供化合物及其藥學組成物，包含式(I)、(II)或(III)：本發明亦提供藉由投藥治療上有效量之所提供的式(I)、(II)或(III)之化合物或其藥學組成物至有需要的病患，以治療與過量FAAH活性有關之病況的方法。此外，本發明提供藉由投藥治療上有效量之所提供的式(I)、(II)或(III)之化合物或其藥學組成物至有需要的病患，以抑制病患體內FAAH的活性之方法。