ALTERATIONS DE L'EXPRESSION DU GENE ERG SPECIFIQUES AU CANCER DE LA PROSTATE, ET PROCEDES DE DETECTION ET DE TRAITEMENT EN FONCTION DE CES ALTERATIONS

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专利权人:

SREENATH, TADURU;PETROVICS, GYORGY; SHIV;SRIVASTAVA, SHIV;SRIVASTAVA;DOBI, ALBERT;SUN, CHEN

发明人:

SRIVASTAVA, SHIV,DOBI, ALBERT,SREENATH, TADURU,PETROVICS, GYORGY,SUN, CHEN

申请号：

CA2664630

公开号：

CA2664630C

申请日:

2007.10.09

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG.

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http://www.ckcest.cn/home/