Site-specific monoconjugated insulinotropic GLP-1 peptides

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专利权人:

Giancarlo Tonon

发明人:

Giancarlo Tonon,Gaetano Orsini,Mauro Sergi,Rodolfo Schrepfer,Pierandrea Esposito

申请号：

US12998708

公开号：

US08580733B2

申请日:

2009.11.04

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention is related to glucagon-like peptide-1 (GLP-1) and analogues insulinotropic peptides, monoconjugated to biocompatible polymeric molecules by enzymatic direct and site-specific transglutamination reaction as well as their pharmaceutical formulations and delivery systems for therapeutical application in dismetabolic pathologies such as type 2 diabetes.

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中国工程科技知识中心

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