The invention relates to an ankle prosthesis (1) comprising a talar implant (2) designed to be implanted. in or on the talus (3), a tibial implant (4) designed to be implanted in or on the tibia (5), and an intermediate implant (6) designed to be interposed between the tibial implant and the talar implant, said intermediate implant (6) being designed to be mounted to move relative to said talar implant (2) at a contact interface (7) in order to allow the ankle to move, said ankle prosthesis (1) being characterised in that it is provided with configurable coupling means (10) designed to enable the intermediate implant (6) to be arranged relative to the tibial implant (4) in a specific configuration chosen from among a plurality of possible configurations.
