WEAVER, GRANT,KULA, JEFF,LIN, BOH, CHANG,BROWN, KAREN,JOHNSON, WESLEY W.,MURPHY, MICHAEL DENNIS
申请号:
CA3022006
公开号:
CA3022006A1
申请日:
2016.05.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The majority of the mortality observed in young pigs occurs between three and five weeks post-weaning for S. suis infections and between four and six weeks post- weaning for H. parasuis and Actinobacillus suis infections. Control of clinical disease associated with S. suis, A. suis and with H. parasuis has been attempted by means of antibiotic treatment, by controlled exposure with live organisms, and by vaccination, using either inactivated commercial or autogenous bacterins administered parenterally. Disclosed herein is an immunogenic composition comprising antigens and a mucosal adjuvant. The composition may be administered to subjects, such as animals, particularly piglets from pre-weaning through the nursery phase, such as from birth or from three to five days of age, to protect from these diseases.