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COMBINED VACCINES FOR PREVENTION OF PIG VIRAL INFECTIONS
专利权人:
СИНОВЕТ (БЕЙДЖИНГ) БАЙОТЕКНОЛОДЖИ КО.;ЛТД (CN)
发明人:
У Хуа (CN),ХЕ Яньлян (CN),СЯ Минци (CN)
申请号:
RU2013158322/10
公开号:
RU2013158322A
申请日:
2012.05.25
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A vaccine composition comprising a vaccine against the virus of reproductive and respiratory syndrome of pigs (PRRSV) and a second vaccine against the virus of pigs, where the vaccine against PRRSV and the second vaccine, essentially do not have immunoinhibition against each other. The vaccine composition of claim 1, further comprising a third vaccine against the swine virus, wherein the PRRSV vaccine, the second vaccine and the third vaccine do not substantially immuno-inhibit against each other. A vaccine composition according to claim 1 or 2, wherein the second vaccine against the swine virus is selected from the vaccine against classical swine fever virus (CSFV) and the vaccine against pseudorabies virus (PRV). The vaccine composition of claim 2, wherein the third swine virus vaccine is selected from a classical swine fever virus (CSFV) vaccine and a pseudo rabies virus (PRV) vaccine, and wherein the third vaccine is different from the second vaccine. The vaccine composition of claim 1, wherein the PRRSV vaccine contains attenuated PRRSV.6. The vaccine composition of claim 5, wherein the attenuated PRRSV contains an Nsp2 nucleotide sequence encoded by a DNA sequence in which, compared to SEQ ID NO: 4, there is no DNA fragment containing at least 50 adjacent nucleotides, where the DNA fragment is at least approximately 80% homologous portion of SEQ ID NO: 8 of the same length. The vaccine composition according to claim 6, where the DNA fragment contains at least 100, at least 120, at least 150, at least 180, at least 200, at least 210, at least 220, at least 230 at least 240, at least 250, at least 260, at least 270, at least 280, at least 290, at1. Вакцинная композиция, содержащая вакцину против вируса репродуктивного и респираторного синдрома свиней (PRRSV) и вторую вакцину против вируса свиней, где вакцина против PRRSV и вторая вакцина, по существу, не оказывают иммуноингибирования в отношении друг друга.2. Вакцинная композиция по п. 1, дополнительно содерж
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