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Recombinant anti-epidermal growth factor receptor antibody composition
专利权人:
シムフォゲン・アクティーゼルスカブ
发明人:
ミッケル・ワンダール・ペダーセン,ミカエル・クラーグ,アダム・エス・ヘイ,ヘレ・ヤコブセン
申请号:
JP2011524186
公开号:
JP5719298B2
申请日:
2009.08.27
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The invention relates to the field of recombinant antibodies for use in human cancer therapy. More specifically the invention provides the use of an antibody composition with two distinct non-overlapping binding specificities to human EGFR. The antibody composition is effecting in treating cancer following treatment with other anti-EGFR antibodies, whether the cancer shows progression during or following the prior treatment or not. The antibody composition can also be used for repeated treatment of recurrent tumors following first-line therapy with the antibody composition of the invention, as the composition does not lead to selection of resistant tumors. A further therapeutic use is the use of an antibody composition of the invention for treatment of cancer that is resistant to known anti-EGFR antibodies.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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