Disclosed is a single-port endoscopic surgical system, comprising a flexible surgical instrument (10), an imaging tool (30) and catheter bodies (40, 50). The flexible surgical instrument (10) comprises a surgical executor (101), a flexible arm body (11), a handle (21) and a proximal structural body (16), the surgical executor (101) being linked to a distal end of the flexible arm body (11), a proximal end of the flexible arm body (11) being linked to the handle (21) through the proximal structural body (16), and the handle (21) driving the flexible arm body (11) to perform a turning motion. The imaging tool (30) comprises an imaging illumination module (301), a turning joint (302) and an imaging tool driving unit (304), the imaging illumination module (301) being linked to a distal end of the turning joint (302), a proximal end of the turning joint (302) being linked to the imaging tool driving unit (304), and the imaging tool driving unit (304) driving the turning joint (302) to perform a turning motion. The catheter bodies (40, 50) are used for guiding the surgical executor (101) at the distal end of the flexible arm body (11) and the imaging illumination module (301) at the distal end of the turning joint (302) to the same region, and simultaneously guiding parts located behind the proximal ends of the flexible arm body (11) and the turning joint (302) in spatially different directions.Linvention concerne un système chirurgical endoscopique à orifice unique, comprenant un instrument chirurgical (10) flexible, un outil (30) dimagerie et des corps (40, 50) de cathéter. Linstrument chirurgical (10) flexible comprend un exécuteur chirurgical (101), un corps de bras (11) flexible, une poignée (21) et un corps structural (16) proximal, lexécuteur chirurgical (101) étant lié à une extrémité distale du corps de bras (11) flexible, une extrémité proximale du corps de bras (11) flexible étant liée à la poignée (21) à travers le corps structural (16) proximal et la poignée