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SECRETION OF ANTIBODIES WITHOUT SIGNAL PEPTIDES FROM BACTERIA
专利权人:
KALOBIOS PHARMACEUTICALS; INC.
发明人:
YARRANTON, GEOFFREY,BEBBINGTON, CHRISTOPHER, R.
申请号:
SG2011092400
公开号:
SG177895A1
申请日:
2006.07.07
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
SECRETION OF ANTIBODIES WITHOUT SIGNAL PEPTIDES FROM BACTERIAAbstractThe present invention is directed generally to compositions and methods for obtaining secretion of antibodies or antigen-binding antibody fragments from prokaryotes without the need for a signal peptide through making use of mutant host strains with altered secretory properties. In particular, the invention provides host cells and methods for obtaining secretion of antibodies or antigen-binding antibody fragments from bacteria without the need for a signal peptide and provides diverse libraries of antibody sequence resulting from such methods. The invention additionally provides diverse libraries.[No Figure]
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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