The inventions discloses a composition comprising at least one N-acetyl lactosamine, at least one sialylated oligosaccharide and at least one fucosylated oligosaccharide, for use in preventing acute respiratory infections (ARI) and/or relieving symptoms of said ARI infections. Preferably said composition is a starter infant formula. Said acute respiratory infection is in particular bronchiolitis or otitis.本發明揭示一種組合物,其包含至少一種N-乙醯基乳糖胺、至少一種唾液酸基化寡醣及至少一種岩藻醣基化寡醣,該組合物用於預防急性呼吸感染(ARI)及/或緩解該等ARI感染之症狀。較佳地,該組合物係初生嬰兒配方(starter infant formula)。該急性呼吸感染具體而言係細枝氣管炎或耳炎。