Comprimé de mésalazine doté d'une dissolution améliorée

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专利权人:

Disphar International B.V.

发明人:

申请号：

EP10174940.6

公开号：

EP2425826A1

申请日:

2010.09.01

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The invention provides a method for preparing a mesalazine enteric coated tablet comprising: (i) granulating a composition comprising mesalazine, a pharmaceutically acceptable salt, or ester thereof, into mesalazine granulates； (ii) tabletting a core composition comprising the mesalazine granulates obtained in (i) to obtain a tablet core； (iii) coating the tablet core obtained in (ii) with at least an enteric coating； where the tablet core hardness is controlled to be comprised between 80 N and 105 N.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/