A bone fixation system, device and method are provided herein. A system may include a bone plate. The bone plate is adapted to be affixed to a bone surface, and comprises a bioactive porous portion. The porous portion is adapted to include bone healing-promoting substances, such as hollow microparticles containing the bone healing-promoting substances embedded in the porous portion. The bone plate further includes at least one attachment portion. In some embodiments, the attachment portion includes a face, which defines indentations, such as dimples, to retain an amount of adhesive.