A vial adapter for use with a syringe having a widened distal syringe tip, and a medicinal vial. The vial adapter includes a top wall, a skirt for telescopically slidingly receiving the medicinal vial, a downwardly depending puncturing spike, and a syringe port opposite the puncturing spike and in flow communication therewith. The syringe port is formed with at least two upright syringe port members for being initially outwardly flexed on the sliding insertion of the widened distal syringe tip into the syringe port and subsequently snapping behind the widened distal syringe tip on its forced full sliding insertion into the syringe port to retain the widened distal syringe tip in said syringe port.
